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FLASH GENE
Symbol EMB contributors: mct - updated : 19-06-2009
HGNC name embigin
HGNC id 30465
Location 5q11.1      Physical location : 49.692.032 - 49.737.234
Synonym name embigin homolog (mouse)
Synonym symbol(s) MGC71745, GP70
DNA
TYPE functioning gene
STRUCTURE 45.20 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 4309 36.7 327 - 2004 15024082
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal   Homo sapiens
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Ig-like V-type (immunoglobulin-like) domains
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to rattus Emb
    homolog to murine Emb
    Homologene
    FAMILY
  • immunoglobulin superfamily (IgSF) class of CAMs
  • a class VI POU domain protein family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • may function as a regulator of cell/ECM interactions during development and in the homeostasis of normal adult tissues
  • enhancing neural cell adhesion molecule-dependent neuromuscular adhesion and thereby modulates neuromuscular junction formation and plasticity
  • may induce terminal spouting by modulating adhesion mediated by other cell adhesion molecule, such as neural cell adhesion molecule (NCAM)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • complex regulating cardiac actin gene expression through interaction of EMB, MEF2D, and the histone transacetylase EP300
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binds as a major complex with MEF2D and the histone transacetylase EP300
  • interacting with SLC16A7
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS