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FLASH GENE
Symbol ELOVL7 contributors: mct/npt - updated : 16-01-2010
HGNC name ELOVL family member 7, elongation of long chain fatty acids (yeast)
HGNC id 26292
Location 5q12.1      Physical location : 60.047.616 - 60.140.101
Synonym name elongation of very long chain fatty acids-like 7
Synonym symbol(s) FLJ23563
DNA
TYPE functioning gene
STRUCTURE 92.48 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text two transcripts encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 3851 - 281 - Tamura (2009)
9 - 3902 - 281 - Tamura (2009)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • ELO family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • preferentially involved in fatty acid elongation of saturated very-long-chain fatty acids (Tamura 2009)
  • could be involved in prostate cancer growth and survival through the metabolism of saturated very-long-chain fatty acids and their derivatives (Tamura 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by the androgen pathway through SREBF1, as well as other lipogenic enzymes (Tamura 2009)
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in prostate cancer (Tamura 2009)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS