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FLASH GENE
Symbol ELOVL1 contributors: - updated : 21-09-2004
HGNC name elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
HGNC id 14418
Location 1p34.1      Physical location : 43.829.072 - 43.833.699
Synonym symbol(s) SSC1, CGI-88
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     7 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two N terminal transmembrane segments in the central hydrophilic region
  • a C terminal region with three transmmembrane segments (TM3)
  • a single HXXHH motif
  • a strong signal (dilysine motifs)
  • HOMOLOGY
    interspecies homolog to C.elegans gene
    homolog to S.cerevisiae feu1/elo2,sur4/elo3
    Homologene
    FAMILY GNS1/SUR4 family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the biosynthesis of very long chain fatty acids and in the pathogenesis of macular degeneration
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS