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FLASH GENE
Symbol ELFN2 contributors: KTN/npt - updated : 26/11/2008
HGNC name extracellular leucine-rich repeat and fibronectin type III domain containing 2
HGNC id 29396
Location 22q13.1      Physical location : 37.764.000 - 37.823.505
Synonym name leucine rich repeat containing 62
Synonym symbol(s) LRRC62, KIAA1904, dJ63G5.3
DNA
TYPE functioning gene
STRUCTURE 59.51 kb     3 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 8379 89.6 820 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepancreas exocrine   moderately
Lymphoid/Immunelymph node   moderately
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
 male systemtestis  moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 22 aa signal peptide
  • five LRR (leucine-rich) repeats
  • a fibronectin type-III domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to dog ELFN2 (97.4 pc)
    homolog to cow ELFN2 (95.4 pc)
    homolog to rattus Elfn2 (95.6 pc)
    homolog to murine Elfn2 (96 pc)
    homolog to chicken ELFN2 (82.1 pc)
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,nucleus
    text
  • single-pass membrane protein
  • basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS