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FLASH GENE
Symbol ELF2 contributors: np/ - updated : 07-12-2005
HGNC name E74-like factor 2 (ets domain transcription factor)
HGNC id 3317
Location 4q31.1      Physical location : 139.978.870 - 140.060.606
Synonym name
  • new Ets-related factor
  • ets family transcription factor ELF2C
  • Synonym symbol(s) EU32, NERF, NERF-2, NERF-1A, NERF-1B
    DNA
    TYPE functioning gene
    STRUCTURE 81.74 kb     9 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 3218 62 581 - 2004 14970218
    acting as a transactivator of the B cell-specific blk promoter
    7 splicing 3171 - 533 highly in thymus 1997 9001422
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus   highly
    Respiratorylung   highly
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectivebone   
    Lymphoid    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • ETS family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
  • RBTN2
  • interacting with RUNX1
  • cell & other
    REGULATION
    Other regulated by angiopoietin-1 in hypoxic cells
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS