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FLASH GENE
Symbol ELAC1 contributors: - updated : 06-05-2002
HGNC name elaC homolog 1 (E. coli)
HGNC id 14197
Location 18q21      Physical location : 48.494.386 - 48.514.489
Synonym name
  • deleted in Ma29
  • tRNA Z (short form)
  • zinc phosphodiesterase ELAC protein 1
  • tRNA 3 endonuclease 1
  • ribonuclease Z 1
  • Synonym symbol(s) D29
    EC.number 3.1.26.11
    DNA
    TYPE functioning gene
    STRUCTURE 20.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - D18S474 - SMAD4 - [D18S816 - ELAC1 - CELSR1 - D18S46 ] - MRO - D18S363 - qter
    Authors Yanaihara (01)
    Text [TSG18A ]
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    two polyadenylation sequences
    mono polymer homomer , dimer
    HOMOLOGY
    intraspecies homolog to E. Coli Elac
    Homologene
    FAMILY RNase Z family
    CATEGORY regulatory , tumor suppressor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • binuclear zinc phosphodiesterase may be be involved in SMAD protein heteromerization, regulation of transcription, DNA-dependent
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binding two zinc or two iron ions
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS