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FLASH GENE
Symbol EIF3K contributors: KTN/npt - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit K
HGNC id 24656
Location 19q13.2      Physical location : 39.109.721 - 39.127.595
Synonym name
  • eukaryotic translation initiation factor 3 subunit k
  • eukaryotic translation initiation factor 3, subunit 12
  • muscle-specific gene M9 protein
  • Synonym symbol(s) M9, ARG134, PTD001, HSPC029, PLAC-24, EIF3S12, PRO1474, eIF-3 p25, eIF-3 p28
    DNA
    TYPE functioning gene
    STRUCTURE 17.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 910 25.1 218 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Endocrineparathyroid   highly
    Reproductivefemale systemovary  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • EIF3S11 family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,adherens
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • tethering microtubule plus ends to the actin-rich cellular cortex
  • involved in the translation initiation
  • CELLULAR PROCESS protein
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • of the eukaryotic transcription initiation factor 3 multisubunit complex
  • of a multiprotein complex at adherens junction
  • INTERACTION
    DNA
    RNA binding to the 40S ribosome and promoting the binding of MET tRNA and mRNA
    small molecule
    protein
  • binding directly to dynein intermediate chain DNCI1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS