protein
| binding to intermediate filament protein K7 (cytokeratin 7) |
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binding to EIF3B |
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SLBP can interact directly with subunit h of EIF3A and with PAIP1 |
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interaction with PAIP1 stabilizes the interaction between PABPC1 and EIF4G, which brings about the circularization of the mRNA |
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PAIP1 act as a translational activator in 5 prime cap-dependent translation by interacting with PABPC1 and the initiation factors EIF4A1 and EIF3A |
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dimer of subunits EIF3A and EIF3C serves as a central scaffold to which most of the other subunits bind |
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RPS6KB1/2 phosphorylate EIF3A to stimulate PAIP1-EIF3A interaction and consequent translation initiation |
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neuron-specific ARHGEF9 interacts with EIF3A, and its binding partner GPHN associates with MTOR |
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EIF4G2 and EIF4G1 share many binding proteins, such as the eukaryotic translation initiation factors EIF3A and EIF4A1 and ribosomal proteins |