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FLASH GENE
Symbol EIF1AD contributors: mct - updated : 28-06-2021
HGNC name eukaryotic translation initiation factor 1A domain containing
HGNC id 28147
Location 11q13.1      Physical location : 65.764.016 - 65.769.578
Synonym symbol(s) MGC11102, OBELIX, haponin
DNA
TYPE functioning gene
STRUCTURE 5.67 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 2887 19 165 - 20158 30180896
6 - 2687 19 165 - 20158 30180896
6 - 2762 19 165 - 20158 30180896
6 - 2786 19 169 - 20158 30180896
6 - 2817 19 165 - 20158 30180896
6 - 2892 19 165 - 20158 30180896
6 - 2916 19 165 - 20158 30180896
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Respiratorylung    
Skin/Tegumentskin    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C-terminal tail of EIF1AD, is likely protein-protein interaction site
  • HOMOLOGY
    Homologene
    FAMILY
  • EIF1AD family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • EIF1AD may bind to the ribosome, similar to its paralog EIF1AX, and could have roles in ribosome biogenenesis or regulation of translation
  • EIF1AD is required for efficient assembly factor recycling and 18S-E processing
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • EIF1AD and LRRC47 bind to late pre-40S particles near RIOK1 and the central rRNA helix 44
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS