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FLASH GENE
Symbol EEFSEC contributors: - updated : 26-07-2005
HGNC name eukaryotic elongation factor, selenocysteine-tRNA-specific
HGNC id 24614
Location 3q21.3      Physical location : 127.872.312 - 128.127.488
Synonym symbol(s) SELB, EFSEC
DNA
TYPE functioning gene
STRUCTURE 255.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node    
Reproductivefemale systemuteruscervix  
Respiratoryrespiratory tractlarynx   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Eefsec
Homologene
FAMILY GTP binding elongation factor family, Selb subfamily
CATEGORY chaperone/stress
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • translation elongation factor activity, bnding GTP, recognizing Sec-tRNA
  • necessary for the incorporation of selenocysteine into proteins
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GTP/GDP binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS