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FLASH GENE
Symbol EEF1B2 contributors: mct - updated : 15-10-2015
HGNC name eukaryotic translation elongation factor 1 beta 2
HGNC id 3208
Location 2q33      Physical location : 207.024.317 - 207.027.653
Synonym name eukaryotic translation elongation factor 1 beta 1
Synonym symbol(s) EF1B2, EF1B, EEF1B1, EEF1B
DNA
TYPE functioning gene
STRUCTURE 3.34 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
ALS2CR19 2q33 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 19 NRP2 2q34 neuropilin 2 LOC391473 2 similar to cyclophilin A FLJ20309 2q33.3 hypothetical protein FLJ20309 NDUFS1 2q33-q34 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) EEF1B2 2q33 eukaryotic translation elongation factor 1 beta 2 GPR1 2q33.3 G protein-coupled receptor 1 KIAA1571 2q34 KIAA1571 protein LOC391474 2 hypothetical gene supported by AK123581 ADAM23 2q33 a disintegrin and metalloproteinase domain 23 LOC200726 2q34 hypothetical LOC200726 LOC391475 2 similar to Down syndrome critical region protein 3 (Down syndrome critical region protein A) LOC130752 KIAA0971 2p23.3-q34 Homo sapiens KIAA0971 protein (KIAA0971), mRNA. CPO 3q12 coproporphyrinogen oxidase (coproporphyria, harderoporphyria) KLF7 2q32 Kruppel-like factor 7 (ubiquitous) LOC389071 2 LOC389071 CREB1 2q32-q34 cAMP responsive element binding protein 1 LOC151194 2q34 similar to hepatocellular carcinoma-associated antigen HCA557b LOC391476 2 similar to PPP1R14B protein FLJ40432 2q34 hypothetical protein FLJ40432 FZD5 2q33-q34 frizzled homolog 5 (Drosophila) LOC389072 2 similar to RIKEN cDNA 9430067K14 gene; Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP) LOC391477 2 similar to ribosomal protein L9; 60S ribosomal protein L9 LOC344471 2q34 similar to dJ999L4.1 (novel protein similar to ribosomal protein L12 (RPL12))
regionally located in the ALS2 region but apparently not mutated
RNA
TRANSCRIPTS type messenger
text variants 1, 2 and 3 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1128 24.6 225 - Sanders
- initiation site 854 24.6 225 - Sanders
- - 900 24.6 225 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text specifically transcribed in brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • EF-1-beta/EF-1-delta family
  • CATEGORY RNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • GDP-GTP exchange factor
  • involved in the transfer of amino ocetylated TRNAs to the ribosome
  • CELLULAR PROCESS nucleotide, transcription
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • both EEF1A1 and EEF1A2 colocalise with all EEF1B2 subunits, in such close proximity that they are highly likely to be in a complex
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS