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FLASH GENE
Symbol EEF1B2 contributors: mct - updated : 15-10-2015
HGNC name eukaryotic translation elongation factor 1 beta 2
HGNC id 3208
Location 2q33      Physical location : 207.024.317 - 207.027.653
Synonym name eukaryotic translation elongation factor 1 beta 1
Synonym symbol(s) EF1B2, EF1B, EEF1B1, EEF1B
DNA
TYPE functioning gene
STRUCTURE 3.34 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
regionally located in the ALS2 region but apparently not mutated
RNA
TRANSCRIPTS type messenger
text variants 1, 2 and 3 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1128 24.6 225 - Sanders
- initiation site 854 24.6 225 - Sanders
- - 900 24.6 225 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text specifically transcribed in brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • EF-1-beta/EF-1-delta family
  • CATEGORY RNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • GDP-GTP exchange factor
  • involved in the transfer of amino ocetylated TRNAs to the ribosome
  • CELLULAR PROCESS nucleotide, transcription
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • both EEF1A1 and EEF1A2 colocalise with all EEF1B2 subunits, in such close proximity that they are highly likely to be in a complex
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS