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FLASH GENE
Symbol ECHDC1 contributors: mct/npt - updated : 04-02-2012
HGNC name enoyl Coenzyme A hydratase domain containing 1
HGNC id 21489
Location 6q22.33      Physical location : 127.609.858 - 127.664.754
Genatlas name
  • ethylmalonyl-CoA decarboxylase
  • Synonym name uncharacterized hypothalamus protein HCDASE
    Synonym symbol(s) dJ351K20.2, DKFZp762M1110
    DNA
    TYPE functioning gene
    STRUCTURE 54.90 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 2354 - 301 - 2008 18326623
    5 - 2301 - 145 - 2008 18326623
    5 - 2132 - 221 - 2008 18326623
    4 - 2079 - 70 - 2008 18326623
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   highly
    Endocrineparathyroid   highly
    Hearing/Equilibriumear   highly
    Nervousbraindiencephalonhypothalamus  
    Skin/Tegumentskin    
    cell lineage
    cell lines melanoma
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Echdc1
    Homologene
    FAMILY
  • enoyl-CoA hydratase/isomerase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may function in fatty acid metabolism
  • involved in mitochondrial fatty acid oxidation
  • may correct a side activity of acetyl-CoA carboxylase, and is involved in metabolite proofreading
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to breast cancer
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS