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FLASH GENE
Symbol DUSP28 contributors: KTN/npt - updated : 30/10/2008
HGNC name dual specificity phosphatase 28
HGNC id 33237
Location 2q37.3      Physical location : 241.499.470 - 241.503.430
Synonym symbol(s) VHP, DUSP26
EC.number 3.1.3.48, 3.1.3.16
DNA
TYPE functioning gene
STRUCTURE 3.96 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1555 18.2 176 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepancreas exocrine   highly
Reproductivefemale systemovary  highly
 male systemtestis  highly
Urinarykidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a tyrosine-protein phosphatase domain
  • HOMOLOGY
    interspecies homolog to cow DUSP28 (83.8 pc)
    homolog to murine Dusp28 (82.3 pc)
    homolog to chicken DUSP28 (64.5 pc)
    Homologene
    FAMILY
  • protein-tyrosine phosphatase family
  • non-receptor class dual specificity subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acting as a protein tyrosine/serine/threonine phosphatase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS