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FLASH GENE
Symbol DSTN contributors: - updated : 11-10-2005
HGNC name destrin (actin depolymerizing factor)
HGNC id 15750
Location 20p11.23      Physical location : 17.550.598 - 17.588.651
Synonym name destrin
Synonym symbol(s) ADF,ACTDP,HGNC15750,bA462D18 2
DNA
TYPE functioning gene
STRUCTURE 38.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1614
- splicing 1746 - 148 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Dstn
Homologene
FAMILY actin-binding proteins ADF family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microfilament
basic FUNCTION This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein actin
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS