| Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
| HGNC | UniGene | Nucleotide | OMIM | UCSC |
| Home Page |
| FLASH GENE |
| Symbol | DRG1 | contributors: - updated : 11-06-2004 |
| HGNC name | developmentally regulated GTP binding protein 1 |
| HGNC id | 3029 |
|
|
| Location | 22q12.2 Physical location : 31.795.538 - 31.830.171 |
| Synonym name | neural precursor cell expressed, developmentally down-regulated 3 |
| Synonym symbol(s) | NEDD3, DRG |
| DNA |
| TYPE | functioning gene |
| STRUCTURE | 34.00 kb 9 Exon(s) |
|
| 10 Kb 5' upstream gene genomic sequence study |
|---|
| MAPPING | cloned | Y | linked | N | status | provisional |
| Map | see PIB5PA |
| RNA |
| TRANSCRIPTS | type | messenger |
|---|
| EXPRESSION |
| Type |
| constitutive of |
| expressed in | (based on citations) |
| organ(s) |
| cells |
|
| cell lineage |
| cell lines |
| fluid/secretion |
| at STAGE |
| PROTEIN |
| PHYSICAL PROPERTIES |
| STRUCTURE |
motifs/domains
|
| HOMOLOGY |
| interspecies | homolog to murine Nedd3 |
| Homologene |
| FAMILY | NDRG gene family |
| CATEGORY | regulatory , signaling |
SUBCELLULAR LOCALIZATION
| plasma membrane |
| intracellular |
| intracellular,cytoplasm |
| basic FUNCTION | a negative involment in the metastatic process in prostate cancer |
| CELLULAR PROCESS |
| PHYSIOLOGICAL PROCESS |
| PATHWAY |
| metabolism |
| signaling |
| a component |
| INTERACTION |
| DNA |
| RNA |
| small molecule |
| protein | |
|
|
| cell & other |
| REGULATION |
| induced by | various chemical agents and antineoplastic drugs such as tunicamycin, mercaptoethanol and homocysteine |
| Other | developmentally regulated |
| ASSOCIATED DISORDERS |
| corresponding disease(s) |
| Susceptibility |
| Variant & Polymorphism | |
|
| Candidate gene | metastasis suppressor gene for prostate cancer that may serve as an useful prognostic marker |
| Marker | |
| Therapy target | |
| ANIMAL & CELL MODELS |