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FLASH GENE
Symbol DPP3 contributors: mct - updated : 02-04-2008
HGNC name dipeptidylpeptidase 3
HGNC id 3008
Location 11q12-q13.1      Physical location : 66.247.879 - 66.277.130
Synonym name dipeptidyl arylamidase III
Synonym symbol(s) DPPIII, FLJ11387, FLJ22331
EC.number 3.4.14.4
DNA
TYPE functioning gene
STRUCTURE 22.00 kb     14 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
18 - 2694 - 737 - Gevaert (2005)
18 - 2697 - 737 - Gevaert (2005)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouth   highly
Lymphoid/Immunespleen   highly
Reproductivefemale systemuteruscervix highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a novel zinc binding HExxGH similar to that of the zincins
conjugated MetalloP
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • removing N terminal dipeptides from dipeptidyl 2-naphtylamide angiotensin or enkephalin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS