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FLASH GENE
Symbol DPH5 contributors: mct/npt - updated : 01-07-2010
HGNC name DPH5 homolog (S. cerevisiae)
HGNC id 24270
Location 1p21.2      Physical location : 101.455.179 - 101.491.362
Synonym name
  • AD-018 protein
  • diphthamide biosynthesis methyltransferase
  • protein x 0011
  • diphthine synthase
    • Synonym symbol(s) CGI-30, AD-018, HSPC143, MGC61450, NPD015
    EC.number 2.1.1.98
    DNA
    TYPE functioning gene
    STRUCTURE 36.18 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1828 - 285 - Liu (2004)
    8 - 1807 - 284 - Liu (2004)
    8 - 1810 - 285 - Liu (2004)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemuteruscervix  
    Respiratoryrespiratory tractlarynx   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to rattus LOC295394
    Homologene
    FAMILY
  • diphtine synthase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • methyltransferase activity
  • peptidyl-diphtamide biosynthesis from peptidyl histidine
  • acting in diphthamide biosynthesis (Webb 2008)
    • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism other
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS