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FLASH GENE
Symbol DNALI1 contributors: npt/mct - updated : 22-01-2014
HGNC name dynein, axonemal, light intermediate chain 1
HGNC id 14353
Location 1p35.1      Physical location : 38.022.519 - 38.032.457
Synonym name
  • dynein,axonemal,light chain 1
  • dynein, axonemal, light intermediate polypeptide 1
  • inner dynein arm, homolog of clamydomonas
  • dJ423B22.5 (axonemal dynein light chain (hp28))
  • Synonym symbol(s) DNAL1, P28, dJ423B22.5
    DNA
    TYPE functioning gene
    STRUCTURE 9.94 kb     6 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LSM10 1p34.3 U7 snRNP-specific Sm-like protein LSM10 NOR1 1p34.3 oxidored-nitro domain-containing protein MRPS15 1p35-p34.1 mitochondrial ribosomal protein S15 CSF3R 1p34.2-p34.1 colony stimulating factor 3 receptor (granulocyte) GRIK3 1p34.1 glutamate receptor, ionotropic, kainate 3 FLJ23231 1p34.2 hypothetical protein FLJ23231 FLJ11730 1p35.3-p33 hypothetical protein FLJ11730 SNIP1 1p34.2 Smad nuclear interacting protein DNALI1 1p35.1 dynein, axonemal, light intermediate polypeptide 1 HUMAUANTIG 1p34.2 nucleolar GTPase FLJ40906 1p34.2 hypothetical protein FLJ40906 FLJ20508 1p34.2 hypothetical protein FLJ20508 CDCA8 1p34.2 cell division cycle associated 8 FLJ33655 1p34.2 hypothetical protein FLJ33655 LOC391026 1 similar to actinin, alpha 4 LOC391027 1 similar to chromosome 14 open reading frame 138 FLJ31434 1p34.2 hypothetical protein FLJ31434 FLJ45459 1p34.2 FLJ45459 protein SF3A3 1p34.1 splicing factor 3a, subunit 3, 60kDa FHL3 1p34.2-p32.3 four and a half LIM domains 3 CGI-94 1p34.2 comparative gene identification transcript 94 POU3F1 1p34.1 POU domain, class 3, transcription factor 1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 2663 - 280 - 2006 16496424
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis  predominantly Homo sapiens
     male systemprostate  highly
    Respiratoryrespiratory tracttrachea  highly Mus musculus
    Urinarykidney   highly
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductivespermatid Mus musculus
    Reproductivespermatocyte Mus musculus
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • inner dynein arm light chain family
  • CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • essential for motility of cilia and flagella
  • function as an axonemal dynein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein C-terminal part of the cytoplasmic dynein heavy chain 1 identified as a putative interacting polypeptide of DNALI1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS