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FLASH GENE
Symbol DNAJC4 contributors: npt/ - updated : 07-07-2008
HGNC name DnaJ (Hsp40) homolog, subfamily C, member 4
HGNC id 5271
Location 11q13.1      Physical location : 63.997.752 - 64.001.752
Synonym name
  • multiple endocrine neoplasia type 1 candidate protein
  • number 18
  • heat shock 40kD protein 2
  • DnaJ-like protein HSPF2
  • Synonym symbol(s) DANJC4, MCG18, HSPF2, MGC19482, MGC57189, MGC71863
    DNA
    TYPE functioning gene
    STRUCTURE 3.85 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC144097 11q13.1 hypothetical protein BC007540 MARK2 11q12-q13 MAP/microtubule affinity-regulating kinase 2 LOC283248 11q13.1 hypothetical protein LOC283248 FLJ13848 11q13.1 hypothetical protein FLJ13848 COX8 11q13.1 cytochrome c oxidase subunit VIII OTUB1 11q13.1 OTU domain, ubiquitin aldehyde binding 1 LRP16 11q11 LRP16 protein LOC387776 11 LOC387776 FLRT1 11q12-q13 fibronectin leucine rich transmembrane protein 1 STIP1 11q13.2 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) URP2 11q13.1 UNC-112 related protein 2 short form MGC11134 11q13.1 tRNA splicing 2' phosphotransferase 1 MGC13045 11q13.1 hypothetical protein MGC13045 DNAJC4 11q13 DnaJ (Hsp40) homolog, subfamily C, member 4 VEGFB 11q13 vascular endothelial growth factor B FKBP2 11q13.1 FK506 binding protein 2, 13kDa PPP1R14B 11q13 protein phosphatase 1, regulatory (inhibitor) subunit 14B PLCB3 11q13.1-q13.2 phospholipase C, beta 3 (phosphatidylinositol-specific) BAD 11q12.3 BCL2-antagonist of cell death C11ORF4 11cen-q22.3 chromosome 11 hypothetical protein ORF4 KCNK4 11q13 potassium channel, subfamily K, member 4 ESRRA 11q12-q13 estrogen-related receptor alpha HSPC152 11q13.1 hypothetical protein HSPC152 PRDX5 11q13.1 peroxiredoxin 5 FLJ37970 11q12.3 hypothetical protein FLJ37970 RPS6KA4 11q11-q13 ribosomal protein S6 kinase, 90kDa, polypeptide 4 LOC387777 11 LOC387777 FLJ37045 11q13.1 hypothetical protein FLJ37045
    regionally located located approximately 250 bp centromeric of the VEGFB gene
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1300 - 241 - Ohtsuka (2000)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a J domain
  • HOMOLOGY
    interspecies homolog to murine Dnajc4
    homolog to E.coli Dna J
    Homologene
    FAMILY
  • DNAJ/HSP40 family of heat shock proteins
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION
    text membrane-associated
    basic FUNCTION unknown
    CELLULAR PROCESS protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS