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FLASH GENE
Symbol DNAJC21 contributors: mct - updated : 24-08-2016
HGNC name DnaJ (Hsp40) homolog, subfamily C, member 21
HGNC id 27030
Corresponding disease
BMFS3 bone marrow failure syndrome 3
Location 5p13.2      Physical location : 34.929.697 - 34.959.068
Synonym name
  • GS3 protein
  • DnaJ homology subfamily A member 5
  • JJJ1 DnaJ domain protein homolog (S. cerevisiae)
    • Synonym symbol(s) GS3, DNAJA5, JJJ1, BMFS3
    DNA
    TYPE functioning gene
    STRUCTURE 29.43 kb     13 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 6083 62.05 531 - 2004 15067379
    13 - 6218 - 576 - 2004 15067379
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestivestomach   highly
    Reproductivefemale systemovary  highly
    Respiratorylung   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal, pregnancy
    Text placenta, brain
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a DnaJ domain
  • C2H2-type zinc finger motif
    • HOMOLOGY
    interspecies homolog to C.elegans DNJ-17
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    intracellular,nucleus
    basic FUNCTION
  • may be playing play a role in co-operating with Hsp70
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) BMFS3
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS