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FLASH GENE
Symbol DNAJC11 contributors: mct - updated : 26-10-2007
HGNC name DnaJ (Hsp40) homolog, subfamily C, member 11
HGNC id 25570
Location 1p36.31      Physical location : 6.694.227 - 6.761.966
Synonym symbol(s) FLJ10737, dJ126A5.1
DNA
TYPE functioning gene
SPECIAL FEATURE head to head
text located in the head-to-head manner with CAMTA1
STRUCTURE 68.00 kb     16 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3197 - 559 - Xie (2007)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinesmall intestine  highly
Lymphoid/Immunespleen   highly
 thymus    
Reproductivefemale systemuteruscervix  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a DnaJ domain
  • a bipartite NLS
  • a FADH domain
  • a FEMCA domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY tumor suppressor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION candidate tumor suppressor genes of neuroblastoma
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein association with six other proteins, metaxins 1, and 2, CHCHD3, CHCHD6 and SAMM50, IMMT (putative role in protein import related to maintenance of mitochondrial structure)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral somatic mutation      
    in neuroblastoma (Henrich 2007)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS