Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

DNAJB8

contributors: npt - updated : 22/10/2008

HGNC name	DnaJ (Hsp40) homolog, subfamily B, member 8
HGNC id	23699

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3q21.3      Physical location : 128.181.281 - 128.186.091
Synonym symbol(s)	MGC33884, DJ6

DNA

TYPE	functioning gene
STRUCTURE	4.81 kb     3 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed DNAJB8 3 - 2479 26 232 - -

EXPRESSION

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a glycine/phenylalanine (G/F)-rich region
	a cysteine-rich domain
	four motifs resembling a zinc finger domain

HOMOLOGY

Homologene

FAMILY

DNAJ/HSP40 family

CATEGORY

chaperone/stress

SUBCELLULAR LOCALIZATION

basic FUNCTION	with DNAJB6 are superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins
	DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS