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FLASH GENE
Symbol DNAJA4 contributors: mct/npt - updated : 01-09-2008
HGNC name DnaJ (Hsp40) homolog, subfamily A, member 4
HGNC id 14885
Location 15q25.1      Physical location : 78.556.486 - 78.574.536
Synonym name DnaJ/Hsp40 chaperone
Synonym symbol(s) PRO1472, MST104, MSTP104
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3203 - 426 - Ohtsuka (2000)
- - 3064 - 397 - Ohtsuka (2000)
- - 2891 - 370 - Ohtsuka (2000)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrineneuroendocrinepituitary  highly
Nervousnerve   highly
Reproductivemale systemprostate  moderately
Respiratoryrespiratory tracttrachea  highly
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a J domain
  • a CR domain
  • conjugated LipoP , Other
    HOMOLOGY
    Homologene
    FAMILY
  • DnaJ protein family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • SREBF-regulated chaperone involved in the cholesterol biosynthesis pathway
  • CELLULAR PROCESS protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    cholesterol biosynthesis pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS