Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | DMGDH | contributors: mct - updated : 07-04-2020 |
HGNC name | dimethylglycine dehydrogenase |
HGNC id | 24475 |
|
Corresponding disease |
| ||
Location | 5q14.1 Physical location : 78.293.429 - 78.365.449 | ||
Synonym symbol(s) | M2GD, DMGDHD, ME2GLYDH | ||
EC.number | 1.5.99.2/1.5.8.4 |
DNA |
TYPE | functioning gene |
STRUCTURE | 72.11 kb 16 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
| |
|
mono polymer | monomer |
HOMOLOGY |
interspecies | ortholog to rattus Dmgdh (86 pc) |
intraspecies | homolog to SARDH |
Homologene |
FAMILY | |
|
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,matrix |
CELLULAR PROCESS | protein, degradation |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | aminoacid |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
requires flavin adenine dinucleotide (FAD) |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | DMGDHD |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene | candidate gene for non-syndromic cleft lip with or without cleft palate (NSCL/P |
Marker | |
Therapy target
| |
ANIMAL & CELL MODELS |