basic FUNCTION
| playing a role in forebrain and craniofacial development |
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required for the transcriptional control of genes important for endometrial cell differentiation |
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may regulate BCL2 and MYC expression |
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transcription factor that is essential for early development |
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important upstream factor in the carcinogenic pathway of prostate cancer |
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may possess properties of onco-proteins that promote tumor progression, invasion, and metastasis, representing a putative signature marker for inflammatory breast cancer and tumor aggressiveness |
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transcription factor that is absent from most normal adult tissues, but is expressed in a wide variety of malignancies |
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having the ability to counteract key transcriptional control mechanisms of the TGFB1 cytostatic program, which could explain, in part, the resistance of tumors to the antiproliferative effect of TGFB1 |
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plays an important role in epithelial-mesenchymal interactions during embryonic and placental development |