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FLASH GENE
Symbol DLEU7 contributors: mct/npt - updated : 10-02-2009
HGNC name deleted in lymphocytic leukemia, 7
HGNC id 17567
Location 13q14.3      Physical location : 51.286.758 - 51.417.885
Synonym name leukemia-associated protein 7
Synonym symbol(s) FLJ44882, LEU7, MGC138214
DNA
TYPE functioning gene
SPECIAL FEATURE overlapping, tail to tail
text overlapping the 3' end of DLEU1 tail to tail
STRUCTURE 131.13 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 1180 17 160 - Hammarsund (2004)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestine    
Nervousbrain    
Reproductivefemale systembreastmammary gland  
Urinarykidney    
Visualeye    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Dleu7
Homologene
FAMILY
CATEGORY tumor suppressor
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • suppressor of tumor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in B-cell chronic lymphocytic leukemia (CLL), by methylation of the promoter
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS