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FLASH GENE
Symbol DLEU7 contributors: mct/npt - updated : 10-02-2009
HGNC name deleted in lymphocytic leukemia, 7
HGNC id 17567
Location 13q14.3      Physical location : 51.286.758 - 51.417.885
Synonym name leukemia-associated protein 7
Synonym symbol(s) FLJ44882, LEU7, MGC138214
DNA
TYPE functioning gene
SPECIAL FEATURE overlapping, tail to tail
text overlapping the 3' end of DLEU1 tail to tail
STRUCTURE 131.13 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
COX7CP1 13q14-q21 cytochrome c oxidase subunit VIIc pseudogene 1 LOC387924 13 similar to hypothetical protein FLJ10826 GPR38 13q14-q21 G protein-coupled receptor 38 CDADC1 13q14.12 cytidine and dCMP deaminase domain containing 1 FLJ12577 13q14.12 hypothetical protein FLJ12577 SETDB2 13q14 SET domain, bifurcated 2 PHF11 13q14.12 PHD finger protein 11 RCBTB1 13q14 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 ARLTS1 EBRP 13q12-q13 emopamil binding related protein, delta8-delta7 sterol isomerase related protein KPNA3 13q14.3 karyopherin alpha 3 (importin alpha 4) LOC220429 13q14.13 similar to Meningioma-expressed antigen 6/11 (MEA6) (MEA11) C13orf1 13q14 chromosome 13 open reading frame 1 RFP2 13q14 ret finger protein 2 KCNRG 13q14.11 potassium channel regulator DLEU2 13q14.2-q14.3 deleted in lymphocytic leukemia, 2 DLEU1 13q14.2-q14.3 deleted in lymphocytic leukemia, 1 FAM10A4 13q14.3 family with sequence similarity 10, member A4 DLEU7 13q14.13 deleted in lymphocytic leukemia 7 FLJ11712 13q14.13 hypothetical protein FLJ11712 GUCY1B2 13q14.3 guanylate cyclase 1, soluble, beta 2 LOC387925 13 LOC387925 LOC341674 13q14.13 similar to ribosomal protein L5; 60S ribosomal protein L5 FLJ30707 13q14.13 hypothetical protein FLJ30707 DDX26 13q14.12-q14.2 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 LOC220433 13q14.13 similar to ribosomal protein S4, X-linked WDFY2 13q14.12 WD repeat and FYVE domain containing 2 FLJ13639 13q14.2 hypothetical protein FLJ13639 FLJ37307 13q14.2 hypothetical protein FLJ37307 DKFZP434K1172 13q14.2 hypothetical protein DKFZp434K1172 LOC387926 13 hypothetical gene supported by AF338231; BC030655 ATP7B 13q14.3 ATPase, Cu++ transporting, beta polypeptide (Wilson disease) KIAA0266 13q12.2-q13.3 KIAA0266 protein LOC387927 13 similar to BB049667 protein MGC75495 13q14.2 similar to Serine/threonine-protein kinase Nek1 (NimA-related protein kinase 1) NEK3 13q14.2-q21.1 NIMA (never in mitosis gene a)-related kinase 3 LOC387928 13 similar to mitochondrial ribosomal protein S31; imogen 38 TPTEps1 13q14.2 TPTE and PTEN homologous inositol lipid phosphatase pseudogene
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 1180 17 160 - Hammarsund (2004)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestine    
Nervousbrain    
Reproductivefemale systembreastmammary gland  
Urinarykidney    
Visualeye    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Dleu7
Homologene
FAMILY
CATEGORY tumor suppressor
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • suppressor of tumor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in B-cell chronic lymphocytic leukemia (CLL), by methylation of the promoter
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS