basic FUNCTION
| Golgi membrane protein that is expressed in a developmentally regulated manner during mesenchymal and cartilage development in mammals |
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specific marker for the dental follicle ( |
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critical role in protein structure and/or function ( |
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DIPK2A and DIPK2B gene products regulate molecular traffic through the cellular secretory pathway or affect the function of secreted factors, and functional deficits cause disorders with ASD-like symptoms and/or mental retardation |
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induces cardiomyocyte proliferation via a phosphoinositide 3-kinase-protein kinase B-cycle-dependent kinase 7 pathway |
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protects the heart from ischemia-induced damage and promotes cardiomyocyte proliferation |
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DIPK2A, a late endosome- and lysosome-localized protein, binds to VAMP7B, which inhibits the interaction of VAMP7B with STX17 and enhances the binding of STX17 to VAMP7A, thus enhancing autophagosome-lysosome fusion |
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DIPK2A participates in autophagic degradation of mitochondria proteins and alleviates apoptosis |
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