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FLASH GENE
Symbol DIO3OS contributors: - updated : 05-09-2007
HGNC name deiodinase, iodothyronine, type III opposite strand
HGNC id 20348
Location 14q32.31      Physical location : 102.018.559 - 102.022.013
Synonym name
  • uterine-derived 14 kDa protein
  • chromosome 14 open reading frame 134
    • Synonym symbol(s) C14orf134
    DNA
    TYPE chromosome region
    SPECIAL FEATURE antisens
    text antisense orientation with DIO3, and may lie within the structure of the antisense gene, a complex arrangement often observed in imprinted loci
    STRUCTURE 3.00 kb     4 Exon(s)
    regulatory sequence Promoter
    motif repetitive sequence   other
    text structure polyadenylation site
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousnervespinal nervesciatic  
    Reproductivefemale systemuterus   
    Visualeyeanterior segmentiris  
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connective    
    Nervousperipherous   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Nervousoptic nerve
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    interspecies homolog to murine Dio3
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be playing a role in the maintenance of DIO3 preferential monoallelic expression
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional     --over  
    in differentiated adipocytes
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS