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FLASH GENE
Symbol DHX40 contributors: SGE/npt - updated : 26-03-2010
HGNC name DEAH (Asp-Glu-Ala-His) box polypeptide 40
HGNC id 18018
Location 17q23.1      Physical location : 57.642.885 - 57.685.712
Synonym name
  • probable ATP-dependent RNA helicase DHX40
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 40 (RNA helicase)
  • protein PAD
  • Synonym symbol(s) PAD, DDX40, ARG147, FLJ22060, FLJ34015, AF319521
    EC.number 3.6.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 42.82 kb     18 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    TEX14 17q22-q23 testis expressed sequence 14 RAD51C 17q22-q23 RAD51 homolog C (S. cerevisiae) PPM1E 17q23.2 protein phosphatase 1E (PP2C domain containing) TRIM37 17q22-q23 tripartite motif-containing 37 LOC348235 17q23.2 hypothetical protein LOC348235 FLJ11029 17q23.2 hypothetical protein FLJ11029 FLJ10587 17q23.2 hypothetical protein FLJ10587 FLJ37451 17q23.2 hypothetical protein FLJ37451 LOC388403 17 similar to Yippee-like protein 2 (DiGeorge syndrome-related protein FKSG4) DHX40 17q23.2 DEAH (Asp-Glu-Ala-His) box polypeptide 40 CLTC 17q11-qter clathrin, heavy polypeptide (Hc) PRO0456 17q23.2 PRO0456 protein CGI-147 17q23.2 CGI-147 protein VMP1 17q23.2 likely ortholog of rat vacuole membrane protein 1 TUBD1 17q23.2 likely ortholog of mouse tubulin, delta 1 RPS6KB1 17q23.3 ribosomal protein S6 kinase, 70kDa, polypeptide 1 LOC51136 17q23.2 PTD016 protein LOC390805 17 similar to DEAH (Asp-Glu-Ala-His) box polypeptide 40 LOC388404 17 similar to TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein) LOC201201 17q23.2 hypothetical LOC201201 ABC1 17q23.2-q23.3 amplified in breast cancer 1 LOC388405 17 LOC388405 CA4 17q23 carbonic anhydrase IV USP32 17q23.3 ubiquitin specific protease 32 LOC124773 17q23.3 hypothetical protein LOC124773 LOC284166 17q23.3 similar to 60S ribosomal protein L12 APPBP2 17q23 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    18 - 3682 - 779 - Xu (2002)
  • isoform 1
  • - - 3451 - 702 - Xu (2002)
  • isoform 2
  • EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one helicase ATP-binding domain
  • one helicase C-terminal domain
  • HOMOLOGY
    interspecies homolog to murine Dhx40 (97.3pc)
    homolog to rattus Dhx40 (97.3pc)
    Homologene
    FAMILY
  • DEAD box helicase family
  • DEAH subfamily
  • CATEGORY enzyme , regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • probable ATP-dependent RNA helicase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS