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FLASH GENE
Symbol DHX35 contributors: - updated : 16-09-2006
HGNC name DEAH (Asp-Glu-Ala-His) box polypeptide 35
HGNC id 15861
Location 20q11.22-q12      Physical location : 37.590.980 - 37.668.365
Synonym symbol(s) C20orf15, FLJ22759, KAIA0875 , DDX35, DDX40
DNA
TYPE functioning gene
STRUCTURE 77.00 kb     22 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
GHRH 20q11.21 growth hormone releasing hormone MANBAL 20q11.23-q12 mannosidase, beta A, lysosomal-like SRC 20q11.21 v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) RPL7AL4 20q11.2 ribosomal protein L7A-like 4 BLCAP 20q11.2-q12 bladder cancer associated protein NNAT 20q11.2-q12 neuronatin PPIAP3 20q11.23 peptidylprolyl isomerase A (cyclophilin A) pseudogene 3 GLRXP 20q11.2 glutaredoxin (thioltransferase) pseudogene CTNNBL1 20q11.23-q12 catenin, beta like 1 C20orf102 20q11.23 chromosome 20 open reading frame 102 KIAA0406 20q11.21-q12 Homo sapiens KIAA0406 gene product (KIAA0406), mRNA. C20orf77 20q11.21-q12 chromosome 20 open reading frame 77 TGM2 20q11.2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) KIAA1755 20q12 KIAA1755 protein BPI 20q11.23 bactericidal/permeability-increasing protein LBP 20q11.23-q12 lipopolysaccharide binding protein LOC388796 20 LOC388796 LOC128439 20q12 hypothetical gene LOC128439 KIAA1219 20q12 KIAA1219 protein RPS3P2 20q11.2 ribosomal protein S3 pseudogene 2 MGC39724 20q12 hypothetical protein MGC39724 LOC391247 20 similar to DNA replication complex GINS protein PSF2 (HSPC037) (CGI-122) (DC5) LOC343578 20q12 similar to dJ1100H13.4 (putative RhoGAP domain containing protein) VIAAT 20q11.23 vesicular inhibitory amino acid transporter FLJ12785 20q12 hypothetical protein FLJ12785 PPP1R16B 20q11.23-q12 protein phosphatase 1, regulatory (inhibitor) subunit 16B C20orf129 20q11.22-q12 chromosome 20 open reading frame 129 DHX35 20q11.22-q12 DEAH (Asp-Glu-Ala-His) box polypeptide 35 NPM1P19 20q11.23 nucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 19 HSPEP1 20 heat shock 10kDa protein 1 (chaperonin 10) pseudogene 1
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouth   highly
 stomach   highly
Lymphoid/Immunethymus   highly
Nervousbrain    
Reproductivefemale systemuteruscervix highly
 male systemprostate   
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • DEAD/H box (Asp - Glu - Ala - Asp/His)
  • C terminal RNA helicase domain
  • HOMOLOGY
    Homologene
    FAMILY
  • DEAD box helicase family
  • DEAH subfamily
  • CATEGORY enzyme , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION having helicase, ATP binding activities
    CELLULAR PROCESS nucleotide, replication
    nucleotide, recombination
    nucleotide, repair
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA binding
    small molecule
    ATP
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS