Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol DHDH contributors: - updated : 29-11-2004
HGNC name dihydrodiol dehydrogenase (dimeric)
HGNC id 17887
Location 19q13.3      Physical location : 49.436.938 - 49.448.226
Synonym name 3-deoxyglucosone reductase
Synonym symbol(s) HUM2DD
EC.number 1.3.1.20
DNA
TYPE functioning gene
STRUCTURE 11.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
cell lineage
cell lines leiomyosarcoma
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
no homology with other types of dihydrodiiol dehydrogenase
HOMOLOGY
interspecies ortholog to japenese monkey,dog,pig,rabbit
homolog to rattus LOC308583
Homologene
FAMILY medium chain dehydrogenase/reductase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
basic FUNCTION
  • high carbonyl reductase activity
  • NADP(+) dependent oxydation of trans-dihydrodiols of aromatic hydrocarbons to the corresponding catechol
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS detoxification
    text putative detxification enzyme against food-derived reactive dicarbonyl compounds
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    NADP+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS