SUBCELLULAR LOCALIZATION
| intracellular
|
| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endoplasmic reticulum
,rough,smooth |
| intracellular,cytoplasm,organelle,Golgi
|
| intracellular,nucleus
|
text
| concentrated in the nucleus after oxidative challenge |
basic FUNCTION
| catalyzing the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis |
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acting as an antiapoptotic factor in neurons |
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playing a role in protection of cells against amyloid beta peptide toxicity and oxidative stress |
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might be involved in the molecular events of adrenocortical tumorigenesis by facilitating steroid synthesis and cell growth |
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being a key mediator of Ras-induced senescence |
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regulates responses to oncogenic and oxidative stimuli |
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flavin adenine dinucleotide-dependent oxidoreductase regulating responses to oncogenic and oxidative stimuli |
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playing a role in cholesterol biosynthesis, APP processing and Abeta generation |