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FLASH GENE
Symbol DGKQ contributors: npt/ - updated : 15-12-2003
HGNC name diacylglycerol kinase, theta 110kDa
HGNC id 2856
Location 4p16.3      Physical location : 952.675 - 967.344
Synonym name
  • diglyceride kinase theta
  • DAG kinase theta
  • Synonym symbol(s) DAGK4, DAGK, DAGK7, DGK-theta
    EC.number 2.7.1.107
    DNA
    TYPE functioning gene
    STRUCTURE 95.32 kb     26 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    26 - 4653 101 942 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Visualeye    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelial    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three Zn dependent phorboesters/diacylglycerol binding domains
  • a RAS association (Ral GDS/AF-6) domain (RA)
  • a cystein-rich repeat
  • a conserved catalytic domain
  • HOMOLOGY
    Homologene
    FAMILY
  • eukaryotic diacylglycerol kinase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    text colocolizing with phosphatidylinositol 4, 5 biphosphate (PIP(2)) in nuclear speckles
    basic FUNCTION
  • converting diacylglycerol to phosphatidic acid
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS