Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol DENR contributors: mct/ - updated : 20-04-2007
HGNC name density-regulated protein
HGNC id 2769
Location 12q24.31      Physical location : 123.237.370 - 123.255.952
Synonym name smooth muscle cell associated protein-3
Synonym symbol(s) DRP, SMAP-3, DRP1
DNA
TYPE functioning gene
STRUCTURE 18.58 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
ARHF 12q24.31 ras homolog gene family, member F (in filopodia) LOC338799 12q24.31 hypothetical protein LOC338799 KIAA1076 12q24.31 KIAA1076 protein HPD 12q24.1-q24.32 4-hydroxyphenylpyruvate dioxygenase PSMD9 12q24.31-q24.32 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 MGC33630 12q24.31 hypothetical protein MGC33630 BCL7A 12q24.13 B-cell CLL/lymphoma 7A MONDOA 12q21.31 Mlx interactor MGC35140 12q24.31 hypothetical protein MGC35140 B3GNT4 12q24 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 DIABLO 12q24.1-q24.31 diablo homolog (Drosophila) VPS33A 12q24.31 vacuolar protein sorting 33A (yeast) RSN 12q24.3 restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) RPL21P1 12q24.2-q24.3 ribosomal protein L21 pseudogene 1 DKFZp434E2220 12q24.31 hypothetical protein DKFZp434E2220 FLJ11021 12q24.31 similar to splicing factor, arginine/serine-rich 4 KNTC1 12q24.31 kinetochore associated 1 HM74a 12q24.31 G protein-coupled receptor HM74a HM74 12q24.31 G protein-coupled receptor HM74a GPR81 12q24.3 G protein-coupled receptor 81 DENR 12q24.31 density-regulated protein TSP-NY 12q24.31 testis-specific protein TSP-NY HIP1R 12q24 huntingtin interacting protein-1-related FLJ12750 12q24.31 hypothetical protein FLJ12750 ABCB9 12q24.31-q24.32 ATP-binding cassette, sub-family B (MDR/TAP), member 9 FLJ13491 12q24.31 hypothetical protein FLJ13491 ARL6IP4 12q24.31 ADP-ribosylation-like factor 6 interacting protein 4 PITPNM2 12q24.31 phosphatidylinositol transfer protein, membrane-associated 2 FLJ13769 12q24.31 hypothetical protein FLJ13769 MPHOSPH9 12q24.31 M-phase phosphoprotein 9 FLJ38663 12q24.31 hypothetical protein FLJ38663 CDK2AP1 12q24.31 CDK2-associated protein 1 SBNO1 12q24.31 sno, strawberry notch homolog 1 (Drosophila) LOC387893 12 similar to SET domain-containing protein 8 MGC7036 12q24.31 hypothetical protein MGC7036 RNP24 12q24.31 coated vesicle membrane protein DDX55 12q24.31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 EIF2B1 12q24.2-q24.31 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa GTF2H3 12q24.31 general transcription factor IIH, polypeptide 3, 34kDa FLJ12975 12q24.31 hypothetical protein FLJ12975 ATP6V0A2 12q24.31 ATPase, H+ transporting, lysosomal V0 subunit a isoform 2 DNAH10 13q14 dynein, axonemal, heavy polypeptide 10
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 3061 22 198 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumcardiac  
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
life cycle quiescence
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a SUI1 domain
  • HOMOLOGY
    Homologene
    FAMILY
  • DENR family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • LGTN and MCTS1/DENR promote release of tRNA and mRNA from recycled 40S subunits
  • roles for Ligatin and the related interacting proteins MCTS1 and DENR in ribosome recycling and initiation, two linked stages of translation
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text intracellular protein traffic
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by growth
    Other density-regulated protein
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS