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FLASH GENE
Symbol DDX60 contributors: KTN/npt - updated : 13/11/2008
HGNC name DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
HGNC id 25942
Location 4q32.3      Physical location : 169.137.442 - 169.239.958
Synonym name probable ATP-dependent RNA helicase DDX60
Synonym symbol(s) FLJ20035, FLJ10787
EC.number 3.6.1.-
DNA
TYPE functioning gene
STRUCTURE 102.46 kb     38 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
38 - 6029 197.7 1712 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach   moderately
Lymphoid/Immunelymph node   moderately
 thymus   highly
Reproductivefemale systemuterus  predominantly
Respiratoryrespiratory tracttrachea  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  moderately
Connective   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an helicase ATP-binding domain with a DEVH box motif
  • an helicase C-terminal domain
  • HOMOLOGY
    interspecies homolog to dog DDX60 (79 pc)
    homolog to rattus Ddx60 (76.8 pc)
    homolog to murine Ddx60 (75.2 pc)
    Homologene
    FAMILY
  • helicase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acting as an ATP-dependent helicase
  • acting as an hydrolase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule nucleotide,
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS