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FLASH GENE
Symbol DDX27 contributors: npt/ - updated : 04-02-2004
HGNC name DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
HGNC id 15837
Location 20q13.13      Physical location : 47.835.831 - 47.860.612
Synonym name
  • RNA helicase-like protein
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 27
    • Synonym symbol(s) RHLP, PP3241, HSPC259, MGC1018, FLJ12917, FLJ20596,FLJ22238, dJ686N3.1, DKFZp667N057, Rrp3p, MGC1018, MGC163147
    EC.number 3.6.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 24.73 kb     21 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    RPL35AP 20q12-q13.1 ribosomal protein L35a pseudogene NCOA3 20q12 nuclear receptor coactivator 3 SULF2 20q12-q13.1 Homo sapiens similar to glucosamine-6-sulfatases (SULF2), mRNA. SRMP1 20q13.13 spermidine synthase pseudogene 1 LOC388798 20 LOC388798 PREX1 20q12-q13 LOC388798 ARFGEF2 20q13.13 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) SNAP23P 20 synaptosomal-associated protein, 23kDa pseudogene CSE1L 20q13 CSE1 chromosome segregation 1-like (yeast) STAU 20q13.1 staufen, RNA binding protein (Drosophila) ARPC3B 20q13.13 actin related protein 2/3 complex, subunit 3B, 21kDa DDX27 20q13.13 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 KIAA1404 20q13.13 KIAA1404 protein KCNB1 20q13.1 potassium voltage-gated channel, Shab-related subfamily, member 1 PTGIS 20q13.1-q13.3 prostaglandin I2 (prostacyclin) synthase B4GALT5 20q13.1-q13.2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 SNRPFP1 20 small nuclear ribonucleoprotein polypeptide F pseudogene 1 SLC9A8 20q13.13 solute carrier family 9 (sodium/hydrogen exchanger), isoform 8 SPATA2 20q13.1-q13.2 spermatogenesis associated 2 ZNF313 20q13.13 zinc finger protein 313 LOC391256 20 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) SNAI1 20q13.2 snail homolog 1 (Drosophila) LOC149738 20q13.13 hypothetical LOC149738 UBE2V1 20q13.2 ubiquitin-conjugating enzyme E2 variant 1 CEBPB 20q13.1 CCAAT/enhancer binding protein (C/EBP), beta COX6CP2 20 cytochrome c oxidase subunit VIc pseudogene 2 PTPN1 20q13.1-q13.2 protein tyrosine phosphatase, non-receptor type 1 LOC200230 20q13.13 similar to KIAA0386 C20orf175 20 chromosome 20 open reading frame 175 RPL36P2 20q13.1 ribosomal protein L36 pseudogene 2 PARD6B 20q13.13 par-6 partitioning defective 6 homolog beta (C. elegans) BCAS4 20q13.13-q13.2 breast carcinoma amplified sequence 4 TMSL6 20 thymosin-like 6 ADNP 20q13.3-q13.2 activity-dependent neuroprotector PSMD10P 20q13.13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 pseudogene DPM1 20q13.13 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    21 - 2711 89.7 796 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal DEAD box (Asp-Glu-Ala-Asp/His)
  • a SPRY domain
  • a second DEAD box
  • a C terminal helicase domain
    • HOMOLOGY
    Homologene
    FAMILY
  • DEAD box helicase family
  • DDX27/DRS1 subfamily
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • RNA helicase activity (Abdelhaleem 2003)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA binding
    small molecule
  • ATP
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS