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FLASH GENE
Symbol DDT contributors: npt/ - updated : 19-01-2008
HGNC name D-dopachrome tautomerase
HGNC id 2732
Location 22q11.23      Physical location : 24.313.554 - 24.322.019
Synonym name
  • D-dopachrome decarboxylase
  • phenylpyruvate tautomerase II
  • Synonym symbol(s) DOPD, DDCT
    EC.number 4.1.1.84
    DNA
    TYPE functioning gene
    SPECIAL FEATURE
    text tightly linked to GSTT2, in head to head disposition
    STRUCTURE 8.47 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    regionally located closely linked to MIF
    RNA
    TRANSCRIPTS type messenger
    text variants 1 and 2 encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 688 12.6 118 - -
    - - 637 12.6 118 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen    
    Cardiovascularheart    
    Digestiveliver   highly
    Nervousbrain    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumentmelanocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , trimer
    HOMOLOGY
    intraspecies homolog to MIFgene,highly and maybe the same (migration inhibitory factor)
    Homologene
    FAMILY
  • MIF family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • converting L-dopachrome into dihydroxyindole
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS