protein
| UFSP2 interacting with DDRGK1 (possibly interacts with the N-terminal domain of UFSP2 and recruits it to the ER) |
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DDRGK1 interacts with NFKBIA and regulates its stability, thereby regulates the NFKB1 transcriptional activity |
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is an ER membrane protein and a critical component of the ubiquitin-fold modifier 1 (UFM1) system |
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DDRGK1 regulates ERN1 protein stability via its interaction with the kinase domain of ERN1, which is dependent on its ufmylation modification |
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DDRGK1 can directly bind to SOX9 to inhibit its ubiquitination and proteasomal degradation |
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enhances the interaction between SLC25A6 and its E3 ligase and thus promotes its ubiquitination and degradation |