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FLASH GENE
Symbol DCP1B contributors: mct/npt - updated : 26-04-2005
HGNC name DCP1 decapping enzyme homolog B (S. cerevisiae)
HGNC id 24451
Location 12p13.33      Physical location : 2.055.213 - 2.113.677
Synonym name decapping enzyme Dcp1b
Synonym symbol(s) FLJ31638
EC.number 3.-.-.-
DNA
TYPE functioning gene
STRUCTURE 58.46 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
SLC6A13 12p13.3 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 RBBP2 12p11 retinoblastoma binding protein 2 MGC13183 12p13.33 hypothetical protein MGC13183 LOC390279 12 similar to proline-rich protein B4GalNac-T3 12p13.33 beta 1,4-N-acetylgalactosaminyltransferase-transferase-III NINJ2 12p13 ninjurin 2 PRKWNK1 12p13.3 protein kinase, lysine deficient 1 RAD52 12p13.33 RAD52 homolog (S. cerevisiae) ELKS 12p13.3 RAD52 homolog (S. cerevisiae) MGC40195 WNT5B 12p13.3 wingless-type MMTV integration site family, member 5B ADIPOR2 12p13.31 adiponectin receptor 2 CACNA2D4 12p13.33 calcium channel, voltage-dependent, alpha 2/delta subunit 4 DCP1B 12p13.33 decapping enzyme hDcp1b CACNA1C 12p13.33 calcium channel, voltage-dependent, L type, alpha 1C subunit FLJ11117 12p13.33 hypothetical protein FLJ11117 LOC283440 12p13.33 hypothetical LOC283440 LOC341511 12p13.33 similar to 60S ribosomal protein L23a FKBP4 12p13.33 FK506 binding protein 4, 59kDa MDS028 12p13.33 uncharacterized hematopoietic stem/progenitor cells protein MDS028 NRIP2 12p13.33 nuclear receptor interacting protein 2 FOXM1 12p13 forkhead box M1 MGC13204 12p13.33 hypothetical protein MGC13204 TULP3 12p13 tubby like protein 3 TEAD4 12p13.3-p13.2 TEA domain family member 4 LOC387825 12 similar to ribosomal protein L13a; 60S ribosomal protein L13a; 23 kD highly basic protein NET-5 12p13.33 transmembrane 4 superfamily member tetraspan NET-5 PP1057 12p13.3 hypothetical protein PP1057 LOC390280 12 similar to RIKEN cDNA 1110014F12 HRMT1L3 12p13.3 HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 2105 67.6 617 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a poly-gln domain
  • HOMOLOGY
    Homologene
    FAMILY
  • DCP1 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may play a role in the degradation of mRNAs, both in normal turn-over and in nonsense-mediated mRNA decay
  • may be generating m7GDP and 5'-phosphorylated mRNAs
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • binding DCP1A and DCP2
  • important subunits of PBs (processing bodies) and is activated on AU-rich element-mRNAs by the protein ZFP36
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS