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FLASH GENE
Symbol DCAF11 contributors: npt/ - updated : 05-12-2003
HGNC name DDB1 and CUL4 associated factor 11
HGNC id 20258
Location 14q11.2      Physical location : 24.583.905 - 24.594.450
Synonym name
  • WD repeat domain 23
  • WD repeat-containing protein 23
  • Synonym symbol(s) GL014, PRO2389, DKFZp779A1629, WDR23
    DNA
    TYPE functioning gene
    STRUCTURE 10.43 kb     15 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    15 - 4311 61.7 546 - Choe (2009)
    15 - 3663 58.8 520 - Choe (2009)
    lacking an in frame segment in the coding region
    - - 3861 - 546 - Choe (2009)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Nervousbrain    
    Respiratorylung    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text brain
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven WD repeats
  • HOMOLOGY
    interspecies homolog to murine Wdr23
    Homologene
    FAMILY
  • WD repeat family
  • CATEGORY regulatory , structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • regulates SKN-1 target genes downstream from p38 mitogen-activated protein kinase, glycogen synthase kinase 3, and insulin-like receptor pathways (Choe 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS