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FLASH GENE
Symbol DBX2 contributors: KTN/npt - updated : 13/11/2008
HGNC name developing brain homeobox 2
HGNC id 33186
Location 12q12      Physical location : 45.408.538 - 45.444.882
Synonym symbol(s) FLJ16139
DNA
TYPE functioning gene
STRUCTURE 36.34 kb     4 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 2722 36.4 339 - Pierani (2001)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  lowly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an homeobox DNA-binding domain
    • HOMOLOGY
    interspecies homolog to chimpanzee DBX2 (98.8 pc)
    homolog to cow DBX2 (86.1 pc)
    homolog to rattus Dbx2 (77.4 pc)
    homolog to murine Dbx2 (76.8 pc)
    homolog to chicken DBX2 (78.7 pc)
    Homologene
    FAMILY
  • H2.0 homeobox family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in DNA-dependent regulation of transcription
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding to specific sequence
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS