| basic FUNCTION
| playing a role in patterning the central nervous system during embryogenesis |
|
playing a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons |
|
regulating the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons |
|
DBX1-expressing cells have a unique function during head development, notably by controlling cell survival in a non cell-autonomous manner  |
|
has an essential function in assigning midline-crossing identity, thereby contributing crucially to the establishment of the wiring laterality in the developing nervous system |
|
DBX1, is a shared requirement for the specification of hypothalamic nuclei governing a subset of innate behaviors |
|
in a temporally regulated manner, DBX1-derived neurons contribute to molecularly distinct neuronal populations in the LH, Arc and VMH that have been implicated in a variety of hypothalamic-driven behaviors |
|
enrichment of DBX1-lineage neurons in the ventral anterior piriform cortex (PC)that project to the orbitofrontal cortex |
