Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol DAAM2 contributors: npt/mct - updated : 28/11/2008
HGNC name dishevelled associated activator of morphogenesis 2
HGNC id 18143
Location 6p21.2      Physical location : 39.760.792 - 39.872.640
Synonym name
  • cDNA sequence, expressed in brain, >100kDa, related to Drosophila diaphanous protein
  • similar to Mouse p140mDia, a target protein for Rho small GTPase
  • Synonym symbol(s) KIAA0381, MGC90515, dJ90A20A.1, RP1-278E11.1
    DNA
    TYPE anonymous DNA segment
    STRUCTURE 111.85 kb     25 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    GLO1 6p21.1 glyoxalase I DNAH8 6p21 dynein, axonemal, heavy polypeptide 8 GLP1R 6p21 glucagon-like peptide 1 receptor C6orf64 6p21.2 chromosome 6 open reading frame 64 KCNK5 6p21 potassium channel, subfamily K, member 5 KCNK17 6p21.2-p21.1 potassium channel, subfamily K, member 17 KCNK16 6p21.2-p21.1 potassium channel, subfamily K, member 16 C6orf102 6p21.2 chromosome 6 open reading frame 102 DAAM2 6p21.1 dishevelled associated activator of morphogenesis 2 MOCS1 6p21.3-p21.1 molybdenum cofactor synthesis 1 LOC391918 6 similar to ribosomal protein L23 LOC391919 6 similar to tubulin, beta 5 LOC389388 6 LOC389388 KIAA1246 6p21.1 LOC389388 UNC5CL 6p21.1 unc-5 homolog C (C. elegans)-like BZRPL1 6p21.1 benzodiazapine receptor (peripheral)-like 1 APOBEC2 6p21 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 C6orf130 6p21.1 chromosome 6 open reading frame 130 NFYA 6p21.3 nuclear transcription factor Y, alpha LOC221442 6p21.1 hypothetical protein LOC221442 TREML1 6p21.1 triggering receptor expressed on myeloid cells-like 1 TREM2 6p21.1 triggering receptor expressed on myeloid cells 2 C6orf76 6p21.1 chromosome 6 open reading frame 76 LOC285852 6p21.1 hypothetical protein LOC285852
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    25 - 6215 - 1067 - Mungall (2003)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   highly
     nerve   highly
    Reproductivemale systemprostate  highly
    Skin/Tegumentskin   highly
    Visualeye   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • Formin-homology FH1 and FH2 domains, which showed 68.9 p 100 total-amino-acid identity with DAAM1
  • HOMOLOGY
    interspecies homolog to Drosophila diaphanous protein
    Homologene
    FAMILY
  • formin homology family, Formin-homology FDD subfamily
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • being effectors of Wnt signaling during vertebrate development
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS