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FLASH GENE
Symbol CYP4Z1 contributors: - updated : 23-02-2006
HGNC name cytochrome P450, family 4, subfamily Z, polypeptide 1
HGNC id 20583
Location 1p33      Physical location : 47.533.159 - 47.583.992
Synonym name
  • cytochrome P450 4Z1
  • Synonym symbol(s) CYP4A20
    EC.number 1.14.14.1
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 50.00 kb     11 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC388627 1 LOC388627 TSPAN-1 1p34.1 tetraspan 1 FLJ20277 RAD54L 1p32 RAD54-like (S. cerevisiae) MUF1 1p34.1 RAD54-like (S. cerevisiae) UQCRH 1p34.1 ubiquinol-cytochrome c reductase hinge protein MGC22960 1p34 MGC22960 gene FAAH 1p35-p34 fatty acid amide hydrolase LOC391036 1 similar to vitamin D3 hydroxylase associated protein LOC388628 1 hypothetical gene supported by BC021746 OTX3 1p34.1 orthodenticle homolog 3 (Drosophila) FLJ32011 1p34.1 hypothetical protein FLJ32011 MKNK1 1p34.1 MAP kinase-interacting serine/threonine kinase 1 MOB3C ATPAF1 1p33-p32.3 ATP synthase mitochondrial F1 complex assembly factor 1 LOC374973 1p34.1 LOC374973 KIAA0494 1pter-p22.1 LOC374973 CYP4B1 1p34-p12 cytochrome P450, family 4, subfamily B, polypeptide 1 LOC388629 1 similar to cytochrome P450 4Z1 CYP4Z2P 1p34.1-p33 cytochrome P450 4Z2 pseudogene CYP4A11 1p36.1-p32.1 cytochrome P450, family 4, subfamily A, polypeptide 11 CYP4X1 1p33 likely ortholog of rat cytochrome P450 4X1 CYP4Z1 1p33 cytochrome P450 4Z1 LOC284541 1p33 similar to fatty acid omega-hydroxylase CYP4A11 MAP17 1p33 membrane-associated protein 17 TAL1 1p32 T-cell acute lymphocytic leukemia 1 SIL 1p33-p32 TAL1 (SCL) interrupting locus UMP-CMPK  UMP-CMP kinase FOXE3 1p32 forkhead box E3 FOXD2 1p34-p32 forkhead box D2 LOC388630 1 similar to LOC129293 protein
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to chimpanzee LOC456556
    Homologene
    FAMILY cytochrome p450 family
    CATEGORY enzyme , transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • catalyzing the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate
  • involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in breast cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS