Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CYP3A7 | contributors: mct - updated : 05-04-2019 |
HGNC name | cytochrome P450, family 3, subfamily A, polypeptide 7 |
HGNC id | 2640 |
|
Location | 7q21.3-q22.1 Physical location : 99.302.661 - 99.332.819 |
Genatlas name | microsomal monooxygenase |
Synonym name | |
| |
Synonym symbol(s) | CP37, P450-HFLA |
EC.number | 1.14.14.1 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
text | cluster of cytochrome P450 genes |
STRUCTURE | 30.00 kb 13 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | restricted |
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | embryo, fetal, pregnancy |
Text | highly in liver, heart, pregnant uterus |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
conjugated | HemoP |
mono polymer | monomer |
HOMOLOGY |
Homologene |
FAMILY | |
|
CATEGORY | enzyme , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,inner | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,cytosolic,microsome |
basic FUNCTION | |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | electron transport |
PATHWAY |
metabolism | drug , hormone |
signaling |
estriol formation during pregnancy |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, nucleotide, |
NADPH, heme |
protein | flavoprotein P450 oxidoreductase (POR) |
cell & other |
REGULATION |
Other | regulated by Sp1,Sp3,HNF3B,USF1 |
ASSOCIATED DISORDERS |
corresponding disease(s) |
related resource | Human Cytochrome P450 (CYP) Allele Nomenclature Committee |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |