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Symbol CYP3A contributors: - updated : 27-08-2007
HGNC name cytochrome P450, family 3, subfamily A
HGNC id 2635
Location 7q21.3-q22.1      Physical location : -
Genatlas name CYP3A locus including four genes CYP3A4,CYP3A5,CYP3A7,CYP3A43 and three pseudogenes CYP3A7P1 and others (see symbols)
Synonym name
  • peptidyl-prolylcis-transisomerase mitochondrial precursor
  • Synonym symbol(s) CYP3
    EC.number 5.2.1.8
    DNA
    TYPE like-sequence
    STRUCTURE 218.00 kb     13 Exon(s)
    MAPPING cloned Y linked N status confirmed
    regionally located CYP3A cluster located in a 231 kb region
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    conjugated HemoP
    mono polymer monomer
    HOMOLOGY
    Homologene
    FAMILY
  • cytochrome P450 subfamily IIIA
  • multigenic cytochrome P450 superfamily of mixed-function monooxygenases
  • CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • niphedipine (calcium channel blocker) oxidase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport , detoxification
    PATHWAY
    metabolism drug
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
    NADPH, heme
    protein flavoprotein P450 oxidoreductase (POR)
    cell & other
    REGULATION
    induced by glucocorticoids,phenobarbital
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS