basic FUNCTION
| responsible for the iron-regulated ferric reductase activity observed in the duodenum |
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plays a physiological role in both iron and copper uptake, through divalent metal transporter 1 (SLC11A2) and copper transporter 1, respectively (Wyman 2008) |
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act as a ferric reductase that furnishes Fe(II), the specific and selective iron species transported by divalent metal transporter 1 (SLC11A2) in the duodenal enterocytes (Latunde-Dada 2008) |
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can act as a ferric reductase that stimulates iron uptake in Caco-2 cells (Latunde-Dada 2008) |