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FLASH GENE
Symbol CXCL6 contributors: - updated : 30-04-2005
HGNC name chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
HGNC id 10643
Location 4q21      Physical location : 74.702.272 - 74.704.476
Synonym name
  • small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)
  • granulocyte chemotactic protein 2
    • Synonym symbol(s) GCP2, SCYB6
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 2.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - IL8 - CXCL1 / PPBP / PF4 - CXCL5 / CXCL6 - CXCL2 / CXCL3 - CXCL11 - CXCL10 - CXCL9 - qter
    Authors O'Donovanet al. (99)
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Scyb6
    Homologene
    FAMILY intercrine alpha family
    CATEGORY immunity/defense , signaling cytokine
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION playing a chemotactic role for neutrophil granulocytes
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by IL-1alpha stimulation in corneal keratocytes
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS