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FLASH GENE
Symbol CTTNBP2NL contributors: mct - updated : 13-02-2019
HGNC name CTTNBP2 N-terminal like
HGNC id 25330
Location 1p13.2      Physical location : 112.938.799 - 113.003.785
Synonym symbol(s) DKFZp547A023, KIAA1433, FLJ13278
DNA
TYPE functioning gene
STRUCTURE 70.08 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 5901 - 639 - 2013 24218568
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to CTTNBP2
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton
basic FUNCTION
  • PKP2 and CTTNBP2NL function in gap junction communication and influence embryo implantation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • complex striatin-interacting phosphatase and kinase (STRIPAK), can establish mutually exclusive interactions with the cortactin-binding proteins cortactin-binding protein 2 (CTTNBP2)/cortactin-binding protein 2, N-terminal-like (CTTNBP2NL) or with an assembly of sarcolemmal membrane-associated protein (SLMAP)
  • CTTNBP2NL interact with cortactin, and is associated with stress fibers
  • CTTNBP2NL dephosphorylated GJA1
  • CTTNBP2NL interacted with the protein phosphatase 2A catalytic subunit (PPP2CA)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS