Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CTSC | contributors: mct - updated : 20-02-2010 |
HGNC name | cathepsin C |
HGNC id | 2528 |
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Corresponding disease |
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Location | 11q14.2 Physical location : 88.026.760 - 88.070.941 | ||||||
Synonym name | |||||||
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Synonym symbol(s) | DPP1, CPPI, DPPI, JP, JPD | ||||||
EC.number | 3.4.14.1 |
DNA |
TYPE | functioning gene |
STRUCTURE | 44.18 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | pregnancy |
Text | placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , tetramer |
HOMOLOGY |
Homologene |
FAMILY | |
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CATEGORY | enzyme , immunity/defense |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,Golgi | |
intracellular,cytoplasm,organelle,lysosome | |
intracellular,cytoplasm,cytosolic,granule | |
text | cytoplasmic granules in mast cells |
basic FUNCTION | |
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CELLULAR PROCESS | protein, degradation |
PHYSIOLOGICAL PROCESS | immunity/defense |
text | |
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PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
protein |
cell & other |
REGULATION |
activated by | chloride ion,endopeptidases such as CTSL,CTSS |
induced by | interleukin 2,IL2 |
ASSOCIATED DISORDERS |
corresponding disease(s) | PALS , JPD2 , HMS |
Susceptibility | to abdominal aortic aneurysms |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |